Carbon Nanotube Polymer Scaffolds as a Conductive Alternative for the Construction of Retinal Sheet Tissue

نویسندگان

چکیده

With the great success of graphene in biomedical field, carbon nanotubes have attracted increasing attention for different applications ophthalmology. Here, we report a novel retinal sheet composed (CNTs) and poly(lactic-co-glycolic acid) (PLGA) that can enhance cell therapy. By tuning our CNTs to regulate mechanical characteristics retina sheets, were able improve vitro viability ganglion cells derived from human-induced pluripotent stem incorporated into CNTs. Engrafted displayed signs regenerating processes along optic nerve. Compared with PLGA scaffolds, CNT-PLGA tissue has excellent electrical conductivity, biocompatibility, biodegradation. This new biomaterial offers insight injury, repair, regeneration.

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ژورنال

عنوان ژورنال: ACS Chemical Neuroscience

سال: 2021

ISSN: ['1948-7193']

DOI: https://doi.org/10.1021/acschemneuro.1c00242